GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2143950 | 1 | rs4594164 | chr14:35509571 | PPP2R3C | chr14:35554679-35591679:- | 0.27 | 5.01 | 2.49E-6 | Atopic dermatitis |
| THYM | cis | rs4606360 | 1 | rs4606360 | chr1:173699007 | SERPINC1 | chr1:173872943-173886516:- | 0.53 | 5.47 | 3.69E-7 | Subjective well-being |
| THYM | cis | rs7301826 | 1 | rs4619189 | chr12:131313797 | STX2 | chr12:131274149-131323811:- | 0.33 | 5.6 | 2.1E-7 | Plasma plasminogen activator levels |
| THYM | cis | rs2243480 | 1 | rs462853 | chr7:65558167 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 5.41 | 4.64E-7 | Diabetic kidney disease |
| THYM | cis | rs703842 | 1 | rs4646536 | chr12:58157988 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 5.82 | 7.89E-8 | Multiple sclerosis |
| THYM | cis | rs703842 | 1 | rs4646536 | chr12:58157988 | TSFM | chr12:58176536-58191367:+ | -0.26 | -4.49 | 1.97E-5 | Multiple sclerosis |
| THYM | cis | rs7552404 | 1 | rs4646961 | chr1:76217169 | ACADM | chr1:76190043-76229353:+ | 0.3 | 4.24 | 5.21E-5 | Blood metabolite levels;Acylcarnitine levels |
| THYM | cis | rs2243480 | 1 | rs464895 | chr7:65527106 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 5.41 | 4.64E-7 | Diabetic kidney disease |
| THYM | cis | rs2243480 | 1 | rs465359 | chr7:65558164 | CCT6P1 | chr7:65216092-65228661:+ | 0.65 | 5.41 | 4.64E-7 | Diabetic kidney disease |
| THYM | cis | rs4660306 | 1 | rs4660306 | chr1:45978675 | CCDC163P | chr1:45960581-45965646:- | 0.85 | 14.54 | 6.79E-26 | Homocysteine levels |
| THYM | cis | rs2275426 | 1 | rs4660317 | chr1:46326226 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs4660319 | chr1:46341623 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs4660321 | chr1:46366760 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs4660306 | 1 | rs4660870 | chr1:45995231 | CCDC163P | chr1:45960581-45965646:- | -0.76 | -12.14 | 4.87E-21 | Homocysteine levels |
| THYM | cis | rs2275426 | 1 | rs4660898 | chr1:46402171 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |